Oral medications
Dapoxetine (specifically approved for PE), other SSRIs at low doses, and selected combination protocols. Choice depends on whether you want on-demand or daily dosing.
Topical desensitising therapies
Lidocaine-prilocaine creams or sprays applied 5-10 minutes before activity. Effective for many men, with the trade-off of needing to plan ahead.
Injectable therapies
Reserved for refractory cases when oral and topical have failed.